Quixote was written by and for Python programmers who need to develop dynamic web sites while using as much of their existing Python knowledge as possible. In particular, Quixote is not very accommodating of the commonly made distinction between "web designers" and "web developers". If the web designers at your organization are keen to try out a real programming language, then Quixote might provide them with a good introduction to Python; but anyone who doesn't understand what "import a module" or "call a function" means isn't going to get very far with Quixote. Similarly, anyone who expects to use a dedicated, WYSIWYG HTML editor for creating web pages will be left out.
This, incidentally, is completely opposite to the stance taken by most other web application frameworks, which is precisely why we don't like most other web application frameworks. In our limited experience, they all invent an HTML templating language that embeds some sort of programming language in HTML, often with deliberate limitations to prevent naive users from shooting themselves in the feet. This usually ends up being painful and frustrating for programmers who want power and flexibility and are perfectly capable of aiming the gun away from their own feet.