The next Python Conference, PyCon 2007, will be in Dallas, Texas, February 23-25 (Friday through Sunday).
PyCon is a community-oriented conference targeting developers of Python applications and the Python interpreter itself. The organizers aim to make the conference affordable and accessible to all.
PyCon is a great place to get new ideas or to find out what's going in the Python world. It's also a fun place to talk to people you don't normally meet in person (including some of my fellow Googlers!).