It may not be Smalltalk, but Ruby is a very close cousin of Smalltalk - and it's getting the attention of people like Scoble. It's just about breakout time for languages that don't put in handcuffs.

I especially like this point he raises:

On clients, they want to choose the highest-reach platforms. That doesn’t mean a Windows app. Or even an app that runs only in IE. It must run on every variant of Linux and Macintosh too.

You mean, like BottomFeeder?