I have various addons to try to normalize links, but I still run into issues where I do dumb things based on now knowing where a link will be opened.
How many times have I CMD-clicked in a gmail email and two new tabs have opened with the same content.
At this point I think I would like to see a slight subtle change to the cursor that would let me know where the link is going to be opened. Then I can hit modifier keys and know what they are doing as the icon change will be shown.
This would help a lot when I am on other computers that may not be tweaked out in the same way.